abstract：BACKGROUND:Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study is one of a few to evaluate the Biocentric platform for VL quantification in routine practice in Sub-Saharan Africa. METH...

journal_title：BMC infectious diseases

authors： Kerschberger B,Mpala Q,Uribe PAD,Maphalala G,de la Tour R,Kalombola S,Bekele A,Chawinga T,Mliba M,Ntshalintshali N,Phugwayo N,Kabore SM,Goiri J,Dlamini S,Ciglenecki I,Fajardo E

更新日期：2018-11-14 00:00:00

abstract：BACKGROUND:Scrub typhus is a zoonotic disease caused by Orientia tsutsugamushi, a gram-negative intracellular bacterium. Myocarditis and rhabdomyolysis are rare complications of scrub typhus. CASE PRESENTATION:We report a case of scrub typhus, which was simultaneously complicated with myocarditis and rhabdomyolysis. A...

journal_title：BMC infectious diseases

authors： Ki YJ,Kim DM,Yoon NR,Kim SS,Kim CM

更新日期：2018-11-07 00:00:00

abstract：BACKGROUND:Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with similar urogenital syndromes, remain undiagnosed and/or untreated. Some of these pathogens are associated ...

journal_title：BMC infectious diseases

authors： Masha SC,Cools P,Descheemaeker P,Reynders M,Sanders EJ,Vaneechoutte M

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:The East African region is endemic with multiple zoonotic diseases and is one of the hotspots for emerging infectious zoonotic diseases with reported multiple outbreaks of epidemic diseases such as Ebola, Marburg and Rift Valley Fever. Here we present a systematic assessment of published research on zoonotic...

journal_title：BMC infectious diseases

authors： Kemunto N,Mogoa E,Osoro E,Bitek A,Kariuki Njenga M,Thumbi SM

更新日期：2018-11-03 00:00:00

abstract：BACKGROUND:Prenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide post-exposure prophylaxis. We examined the association between oseltamivir use during pregnancy and birth outcomes. METHODS:This was a nationwide registry-based ...

journal_title：BMC infectious diseases

authors： Ehrenstein V,Kristensen NR,Monz BU,Clinch B,Kenwright A,Sørensen HT

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:The first step of designing any genome-based molecular diagnostic test is to find a specific target sequence. The modified genome comparison method is one of the easiest and most comprehensive ways to achieve this goal. In this study, we aimed to explain this method with the example of Mycobacterium tubercul...

journal_title：BMC infectious diseases

authors： Neshani A,Kamali Kakhki R,Sankian M,Zare H,Hooshyar Chichaklu A,Sayyadi M,Ghazvini K

更新日期：2018-10-12 00:00:00

abstract：BACKGROUND:Incomplete virologic suppression results in mutations associated with resistance and is a major obstacle to disease control. We analyzed the genotypic profiles of HIV-1 patients at the time of the first virologic failure and the response to a salvage regimen after 48 weeks. METHODS:This work was a cross-sec...

journal_title：BMC infectious diseases

authors： Oliveira MI,Romão de Souza Junior V,Fernanda de Lacerda Vidal C,Sérgio Ramos de Araújo P

更新日期：2018-10-12 00:00:00

abstract：:The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single dose rifampicin (SDR) as post-exposure prophylaxis (PEP) for contacts of leprosy patients, reduces their risk to develop leprosy by 60%. This...

journal_title：BMC infectious diseases

authors： Mieras LF,Taal AT,van Brakel WH,Cambau E,Saunderson PR,Smith WCS,Prakoeswa CRS,Astari L,Scollard DM,do Nascimento DC,Grosset J,Kar HK,Izumi S,Gillini L,Virmond MCL,Sturkenboom MGG

更新日期：2018-10-05 00:00:00

abstract：BACKGROUND:The live attenuated tetravalent dengue vaccine (CYD-TDV) is licensed using a 0-, 6- and 12-month schedule in dengue-endemic areas. An effective shorter schedule may provide more rapid, optimal protection of targeted populations during vaccine campaigns in dengue-endemic countries. We compared immune response...

journal_title：BMC infectious diseases

authors： Kirstein J,Douglas W,Thakur M,Boaz M,Papa T,Skipetrova A,Plennevaux E

更新日期：2018-09-21 00:00:00

abstract：BACKGROUND:Members of Shewanella species are opportunistic pathogens that are found in marine environments. Currently more than sixty species have been identified, whereas the most commonly clinical cases associated with Shewanella species have involved only two species, i.e., S. algae and S. putrefaciens. We present t...

journal_title：BMC infectious diseases

authors： Zhang F,Fang Y,Pang F,Liang S,Lu X,Kan B,Xu J,Zhao J,Du Y,Wang D

更新日期：2018-09-05 00:00:00

abstract：BACKGROUND:Tuberculosis remains a serious threat to human health as an infectious disease in China. Henan, a most populated province in China, has a high incidence of tuberculosis (TB). Though the genetic diversity of Mycobacterium tuberculosis (MTB) has been investigated in many regions, there have been only a few stu...

journal_title：BMC infectious diseases

authors： Shi J,Zheng D,Zhu Y,Ma X,Wang S,Li H,Xing J

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis is an inflammatory disorder in which the role of bacteria remains uncertain. While sinus outflow obstruction is often an initiating event, mucosal inflammation and dysbiosis may persist or develop in sinuses with widely patent surgical openings. Understanding of the relationship betwee...

journal_title：BMC infectious diseases

authors： Koutsourelakis I,Halderman A,Khalil S,Hittle LE,Mongodin EF,Lane AP

更新日期：2018-08-30 00:00:00

abstract：BACKGROUND:Streptococcus pneumoniae is a commensal of the human upper respiratory tract and a major cause of morbidity and mortality worldwide. This paper presents the distribution of serotypes and antimicrobial resistance in commensal S. pneumoniae strains cultured from healthy carriers older than four years of age in...

journal_title：BMC infectious diseases

authors： Yahiaoui RY,Bootsma HJ,den Heijer CDJ,Pluister GN,John Paget W,Spreeuwenberg P,Trzcinski K,Stobberingh EE

更新日期：2018-08-29 00:00:00

abstract：BACKGROUND:The major factors contributing for nerve damage and permanent disabilities in leprosy are type 1 or reversal reactions (RR) and type 2 or erythema nodosum leprosum (ENL). Gene profiling of leprosy reactions have shown that different pathways are activated during the course of reactions, which is consistent w...

journal_title：BMC infectious diseases

authors： Rêgo JL,de Lima Santana N,Machado PRL,Ribeiro-Alves M,de Toledo-Pinto TG,Castellucci LC,Moraes MO

更新日期：2018-08-24 00:00:00

abstract：BACKGROUND:Dengue infection is an endemic illness in the tropics and it is associated with a wide variety of post infectious complications. With the increasing prevalence of dengue infection in endemic regions, post-infectious neurological complications following dengue infection are now been reported more frequently. ...

journal_title：BMC infectious diseases

authors： Higgoda R,Perera D,Thirumavalavan K

更新日期：2018-08-22 00:00:00

abstract：BACKGROUND:Over 80% of morbidity due to soil-transmitted helminthiasis (STH) occurs in low-income countries. Children under 5 account for 20-30% of the burden in endemic areas. This study assessed the prevalence, intensity and factors associated with STH infections among preschool-age children (PSAC) in Hoima district,...

journal_title：BMC infectious diseases

authors： Ojja S,Kisaka S,Ediau M,Tuhebwe D,Kisakye AN,Halage AA,Mugambe RK,Mutyoba JN

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Schistosomiasis, caused by Schistosoma japonicum, remains one of the most important parasitic diseases, and detection of S. japonicum infections in humans plays a crucial role in control and treatment. However, comparisons between the parasitological and the immunological examinations in the fields of China ...

journal_title：BMC infectious diseases

authors： Deng Y,Qiu C,Ding H,Lu DB

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:During the fifth wave of human H7N9 infections, a novel highly pathogenic (HP) H7N9 variant emerged with an insertion of multiple basic amino acids in the HA cleavage site. Moreover, a neuraminidase inhibitor (NAI) resistance (R292K in NA) mutation was found in H7N9 isolates from humans, poultry and the envi...

journal_title：BMC infectious diseases

authors： Yang Y,Li S,Wong G,Ma S,Xu Z,Zhao X,Li H,Xu W,Zheng H,Lin J,Zhao Q,Liu W,Liu Y,Gao GF,Bi Y

更新日期：2018-08-15 00:00:00

abstract：BACKGROUND:Hand, foot, and mouth disease (HFMD) has been recognized as one of the leading infectious diseases among children in China, which causes hundreds of annual deaths since 2008. In China, the reports of monthly HFMD cases usually have a delay of 1-2 months due to the time needed for collecting and processing cl...

journal_title：BMC infectious diseases

authors： Zhao Y,Xu Q,Chen Y,Tsui KL

更新日期：2018-08-13 00:00:00

abstract：BACKGROUND:Staphylococcus aureus bacteraemia (SAB) causes considerable morbidity and mortality in children. Despite this, its epidemiology and risk factors are poorly understood, with minimal paediatric clinical trial data available to guide clinicians in management. We conducted a pilot study to characterise SAB and v...

journal_title：BMC infectious diseases

authors： Munro APS,Blyth CC,Campbell AJ,Bowen AC

更新日期：2018-08-10 00:00:00

abstract：BACKGROUNDS:Several studies have evaluated the impact of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) combined with antimicrobial stewardship in patients with positive blood cultures; clinical outcomes improved. However, in many hospitals, antimicrobial stewardship is no...

journal_title：BMC infectious diseases

authors： Jeon YD,Seong H,Kim D,Ahn MY,Jung IY,Jeong SJ,Choi JY,Song YG,Yong D,Lee K,Kim JM,Ku NS

更新日期：2018-08-09 00:00:00

abstract：BACKGROUND:Human parechovirus type 3 (HPeV-3) is known to cause cold-like symptoms, diarrhea, or severe infections such as sepsis in infants and children. In adults, HPeV-3 infection is rarely diagnosed because the symptoms are generally mild and self-limiting; however, this infection has been linked to epidemic myalgi...

journal_title：BMC infectious diseases

authors： Nakamura K,Saito K,Hara Y,Aoyagi T,Kitakawa K,Abe Y,Takemura H,Ikeda F,Kaku M,Kanemitsu K

更新日期：2018-08-07 00:00:00

abstract：BACKGROUND:Some children are prone to recurrent invasive pneumococcal disease (rIPD) and of these, some respond insufficiently to standard pneumococcal vaccination. Little is known about how to handle these children and if they benefit from additional vaccination. Here, we present results from a nationwide study of ped...

journal_title：BMC infectious diseases

authors： Ingels HAS,Kantsø B,Slotved HC

更新日期：2018-08-06 00:00:00

abstract：BACKGROUND:Klebsiella pneumoniae bloodstream infections (BSIs) occur with significant prevalence and high mortality worldwide. Antimicrobial resistance and virulence are two main factors participating in the pathogenicity of K. pneumoniae. Here we investigated the prevalence of blaKPC and virulence factors in K. pneumo...

journal_title：BMC infectious diseases

authors： Xu M,Fu Y,Kong H,Chen X,Chen Y,Li L,Yang Q

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Refugees in sub-Saharan Africa face both the risk of HIV infection and barriers to HIV testing. We conducted a pilot study to determine the feasibility and acceptability of home-based HIV testing in Nakivale Refugee Settlement in Uganda and to compare home-based and clinic-based testing participants in Nakiv...

journal_title：BMC infectious diseases

authors： O'Laughlin KN,He W,Greenwald KE,Kasozi J,Chang Y,Mulogo E,Faustin ZM,Njogu P,Walensky RP,Bassett IV

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Underlying coinfections may complicate infectious disease states but commonly go unnoticed because an a priori clinical suspicion is usually required so they can be detected via targeted diagnostic tools. Shotgun metagenomics is a broad diagnostic tool that can be useful for identifying multiple microbes sim...

journal_title：BMC infectious diseases

authors： Birdsell DN,Özsürekci Y,Rawat A,Aycan AE,Mitchell CL,Sahl JW,Johansson A,Colman RE,Schupp JM,Ceyhan M,Keim PS,Wagner DM

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Rosacea is an inflammatory disease affecting the central part of face characterized by persistent or recurrent episodes of erythema, papules, pustules and telangiectasias of unknown etiology. Helicobacter pylori (H. pylori) is a gram-negative bacillus, which is one of the main causes of chronic gastritis, ga...

journal_title：BMC infectious diseases

authors： Yang X

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Antiretroviral therapy dramatically reduced HIV-related morbidity and mortality, prolonging the lifespan of HIV-infected patients. Greater duration of infection and exposure to antiretroviral therapy makes these patients susceptible to traditional cardio-metabolic risk factors and pathologies. The optimal di...

journal_title：BMC infectious diseases

authors： Coelho AR,Moreira FA,Santos AC,Silva-Pinto A,Sarmento A,Carvalho D,Freitas P

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Efficient and effective strategies for identifying cases of active tuberculosis (TB) in rural sub-Saharan Africa are lacking. Household contact tracing offers a potential approach to diagnose more TB cases, and to do so earlier in the disease course. METHODS:Adults newly diagnosed with active TB were recrui...

journal_title：BMC infectious diseases

authors： Little KM,Msandiwa R,Martinson N,Golub J,Chaisson R,Dowdy D

更新日期：2018-07-04 00:00:00

abstract：BACKGROUND:The epidemiology of maternal and infant Group B streptococcus (GBS) colonization is poorly understood in China. The aim of this study is to explore the prevalence and risk factors associated with maternal and infant GBS colonization in Western China. METHODS:From January 2017 to June 2017, a prospective stu...

journal_title：BMC infectious diseases

authors： Chen J,Fu J,Du W,Liu X,Rongkavilit C,Huang X,Wu Y,Wang Y,McGrath E

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:Schizophyllum commune, a basidiomycetous fungus, is a common invader of rotten wood. This fungus rarely causes mycotic disease in humans, especially cutaneous infection. In this paper, we describe the first case of cutaneous granuloma caused by S. commune in a Chinese woman. CASE PRESENTATION:A 25-year-old ...

journal_title：BMC infectious diseases

authors： Tian L,Mu Y,Zhang H,Su X,Yang C,Shu X,Qing D

更新日期：2018-06-26 00:00:00

abstract：BACKGROUND:The burden of mother-to-child transmission rate of HIV is high and risk factors are common in Ethiopia. This systematic review and meta-analysis intended to provide the pooled estimation of mother-to-child transmission rate and its risk factors in Ethiopia. METHODS:We searched PubMed, Google Scholar, EMBASE...

journal_title：BMC infectious diseases

authors： Endalamaw A,Demsie A,Eshetie S,Habtewold TD

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Retention in care and adherence to the treatment is very important for the success of the program while access for treatment is being scaled up. Without more precise data about the rate of loss to follow up as well the characteristics of those who disengage from the treatment appropriate interventions to inc...

journal_title：BMC infectious diseases

authors： Seifu W,Ali W,Meresa B

更新日期：2018-06-18 00:00:00

abstract：BACKGROUND:Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within age strata using surveillance data from twenty-nine countries during 1999-2014 (N=358,796 influenza cases). METHODS:For each virus, we...

journal_title：BMC infectious diseases

authors： Caini S,Spreeuwenberg P,Kusznierz GF,Rudi JM,Owen R,Pennington K,Wangchuk S,Gyeltshen S,Ferreira de Almeida WA,Pessanha Henriques CM,Njouom R,Vernet MA,Fasce RA,Andrade W,Yu H,Feng L,Yang J,Peng Z,Lara J,Bruno A,d

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:Brucella abortus is a highly pathogenic zoonotic agent, tempting for the development of a rapid diagnostic method to enable adequate treatment and prevent further spread. Enrichment of the bacteria is often used as a first step in diagnostics to increase the bacterial number above the detection limit of the ...

journal_title：BMC infectious diseases

authors： Kaden R,Ferrari S,Jinnerot T,Lindberg M,Wahab T,Lavander M

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Cryptococcus gattii is known to be an etiologic agent of human cryptococcosis, particularly in immunocompetent persons. C. gattii infection usually involves the central nervous system, the respiratory tract, or may be disseminated. Here we report an atypical manifestation of C. gattii infection in a patient ...

journal_title：BMC infectious diseases

authors： Dhitinanmuang W,Chongtrakool P,Jitmuang A

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:Armed conflicts are a major contributor to injury and death globally. Conflict-related injuries are associated with a high risk of wound infection, but it is unknown to what extent infection directly relates to sustainment of life and restoration of function. The aim of this study was to investigate the outc...

journal_title：BMC infectious diseases

authors： Älgå A,Wong S,Shoaib M,Lundgren K,Giske CG,von Schreeb J,Malmstedt J

更新日期：2018-05-22 00:00:00

abstract：BACKGROUND:Tuberculosis (TB) is the major cause of death in Human Immunodeficiency Virus (HIV)-infected individuals. However, diagnosis of TB in HIV remains challenging particularly when HIV infection is advanced. Several gene signatures and serum protein biomarkers have been identified that distinguish active TB from ...

journal_title：BMC infectious diseases

authors： Verma S,Du P,Nakanjako D,Hermans S,Briggs J,Nakiyingi L,Ellner JJ,Manabe YC,Salgame P

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:Antimicrobial resistance (AMR) is a major challenge for global health care. Pharmacists play a key role in the health care setting to help support the quality use of medicines. The education, training, and experiences of pharmacy students have the potential to impact on patterns of antibiotic use in communit...

journal_title：BMC infectious diseases

authors： Sakeena MHF,Bennett AA,Jamshed S,Mohamed F,Herath DR,Gawarammana I,McLachlan AJ

更新日期：2018-05-08 00:00:00

abstract：BACKGROUND:Benefits using the 13-valent pneumococcal conjugate vaccine (PCV13) in adults are controversial. This study investigated clinical effectiveness of PCV13 vaccination in preventing hospitalisation from pneumonia among middle-aged and older adults. METHODS:Population-based cohort study involving 2,025,730 indi...

journal_title：BMC infectious diseases

authors： Vila-Corcoles A,Ochoa-Gondar O,de Diego C,Satue E,Aragón M,Vila-Rovira A,Gomez-Bertomeu F,Magarolas R,Figuerola-Massana E,Raga X,Perez MO,Ballester F

更新日期：2018-04-27 00:00:00